Quest for Infamy is a point-and-click adventure with role-playing elements, inspired by classic Sierra games such as Quest for Glory. Players follow Roehm, a roguish anti-hero who arrives in a new valley while fleeing trouble and gets drawn into its affairs.

Players can pursue one of several character paths, fight in turn-based combat and build up stats alongside traditional adventure-game puzzles. Its hand-drawn pixel art, sharp humor and large voiced cast give it a strong retro flavor.